English name: Bakuchiol Cas : 10309-37-2 MF: C18H24O MW 256.389 Source: Psoralea corylifolia Linn. Physical properties: Oil Purity: 90% Analytical method: HPLC-DAD or/and HPLC-ELSD
Psoralen, isopsoralen and 8-methoxypsoralen are photosensitive substances in Psoralea corylifolia. Therefore, UVA combined with sunshine or topical irradiation can promote the formation of skin melanin. Psoralea corylifolia can activate tyrosinase up to 44.9%. Psoralea corylifolia extract of 95% ethanol has obvious activation on tyrosinase, and tyrosinase is the key enzyme of melanin synthesis in human body. Therefore, Psoralea corylifolia can increase the speed and quantity of melanin production by increasing the activity of tyrosinase. Psoralen B can dilate blood vessels, improve local tissue nutrition, increase skin pigmentation, promote the synthesis of skin melanin, and make it sink to the subcutaneous.
1.Old people are often used to cure the wound, furuncle carbuncle swollen poison, snakebite can also be used as an antidote, can directly kill cells infected by bacteria, analgesic, antibacterial, anti-inflammatory, antiviral effect. 2.Herbal magic plant drugstore after the years of research, found that it can full in just a few hours to kill to acne acne propionic acid bacillus, even the heavy lumps, nodules, cysts, blain blain, insist to use can eliminate blain to imprint.
1. The vitiligo liniment composed of psoralen, plum, Angelica dahurica, cinnamon and other multiflavor drugs has the function of warming meridians and dredging collaterals, nourishing blood and dispelling wind; while 8-methoxypsoralen 0.05%/ml and acetic acid skin relaxant 0.0125%/ml can be used externally to treat vitiligo, with definite curative effect and good clinical effect. 2. Psoralen tincture, which is mainly prepared by psoralen and isopsoralen, can increase tyrosinase activity in melanocytes, promote biochemical synthesis and operation of melanin, and promote skin color to return to normal. 3.8- methoxalin liposome gel, because MOP rarely entered the blood circulation, reduced many adverse reactions (retinal toxicity and hepatotoxicity), and increased its retention time and retention in the basal layer of epidermis, thus promoting melanin synthesis. 4. Psoralea corylifolia injection contains 8-methoxypsoralen, which can increase the sensitivity of skin to ultraviolet radiation. After ultraviolet irradiation, it can effectively inhibit DNA synthesis of epidermal keratinocytes, thereby inhibiting excessive proliferation of psoriatic keratinocytes and achieving therapeutic purposes.
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